John 'Hombre' Russell is a white man raised by the Apaches on an Indian reservation and later by a white man in town. As an adult he prefers to live on the reservation. He is informed that he has inherited a lodging-house in the town. He goes to the town and decides to trade the place for a herd. He has to go to another city. The only stagecoach is one being hired for a special trip paid by Faver and his wife Audra. As there are several seats others join the stagecoach making seven very different passengers in all. During the journey they are robbed. With the leadership of John Russell they escape with little water and the money that the bandits want. They are pursued by the bandits. As they try to evade the bandits they reveal their true nature in a life threatening situation.

High-strung race car driver Alan Colby is trying to recover from a serious head injury. Alan and his lovely new wife Denise go on vacation to the South of France for some much needed rest and relaxation. But Alan is having trouble resisting his more violent impulses. Suave local psychiatrist David Prade offers to help Alan out.

Sgt. Howie travels to Summerisle to investigate the disappearance of a young girl. He discovers that the locals are weird and unhelpful, and becomes determined to get to the bottom of the disappearance.

Pope Julius is eager to leave behind works by which he will be remembered. To this end he cajoles Michelangelo into painting the ceiling of the Sistine Chapel. When not on the battlefield uniting Italy, the Pope nags Michelangelo to speed up his painful work on the frescoes.